Information for Authors

American Journal of Stem Cells (AJSC, ISSN: 2160-4150) is an open access online journal dedicated to publication of original work in all
areas of stem cell research. AJSC is primarily devoted to original research papers (Main Research Articles and Brief Communications),
and will also publish traditional Review articles and limited number of important Case Reports. The goal of AJSC is to provide a forum for
rapid dissemination of novel discoveries in basic and clinical studies on all aspects of Stem Cells.

SUBMISSION OF MANUSCRIPT

General Policy

All manuscripts are submitted with the understanding that they have not been published elsewhere (except in the form of an abstract or
as part of a published lecture or thesis) and are not currently under consideration for publication by another journal. It is the responsibility
of the corresponding author to ensure that all authors have contributed to, read and approved the final manuscript for submission. The
authors should keep a copy of manuscript submitted in case of revision, rejection, loss or damage. Receipt of manuscript will be
acknowledged and a decision regarding acceptance made as soon as possible. Accepted manuscripts may be subject to editorial
revision without notice.

Peer Review Policy

All manuscripts are subject to peer review and are expected to meet the rigorous standards of academic excellence. Authors should
provide 4 potential peer reviewers with detailed contact information including e-mail address. Authors may also nominate 2 peers that
they request are not sent the article for peer review for conflicts of interest or other appropriate reasons – in such instances some
reasonable justification must be given. These should be experts in their field of study, who will be able to provide an objective
assessment of the manuscript. If not provided, potential reviewers will be identified by their publication record or recommended by the
Editorial Board members.

Copyright Policy

By submitting a manuscript to AJSC, all authors agree that all copyrights of all materials included in the submitted manuscript will be
exclusively transferred to the publisher - e-Century Publishing Corporation once the manuscript is accepted.

Once the paper is published, the copyright will be released by the publisher under the “Creative Commons Attribution Noncommercial
License”, enabling the unrestricted non-commercial use, distribution, and reproduction of the published article in any medium, provided
that the original work is properly cited. If the manuscript contains a figure or table reproduced from a book or another journal article, the
authors should obtain permission from the copyright holder before submitting the manuscript, and be fully responsible for any legal
and/or financial consequences if such permissions are not obtained.

All PDF, XML and html files for all articles published in this journal are the property of the publisher, e-Century Publishing Corporation
(www.e-Century.org). Authors and readers are granted the right to freely use these files for all academic purposes. By publishing paper
in this journal, the authors grant the permanent right to the publisher to use any articles published in this journal without any restriction
including, but not limited to academic and/or commercial purposes. If you are interested in using PDF, html, XML files or any art works
published in this journal for any commercial purposes, please contact the publisher at business@e-century.org.

Use of Human Subjects/Human Tissue and/or Animal Policy

Experiments involving human subjects should be done in accordance with the relevant ethical and legal standards established and
accepted by their host institution or in accordance with the Helsinki Declaration of 1975, or the Guidelines of Office for Human Research
Protections (OHRP) Human Subject Protections or equivalent. For studies that involved human subjects, when informed consent has
been obtained it should be indicated in the manuscript.

Experiments involving animals should follow the appropriate institution or the National Research Council Guide for the care and use of
laboratory animals.

Units and Abbreviations

System International (SI) units should be used for all measurements. All abbreviations should be explicitly defined at their first
occurrence except for those internationally acceptable. Abbreviations used in the genetic association reports will need to follow the
conventions detailed in the specific information requirements for genetic association reports. Any articles that involve the description of
enzymes will require the inclusion of the appropriate EC (Enzyme Commission) number as recommended by the Nomenclature
Committee of the International Union of Biochemistry and Molecular Biology (IUBMB).

Disclaimer

While the advice and information in the article are believed to be true and accurate on the date of its going to press, neither the authors
nor the editors can accept any legal responsibilities for any errors or omissions that may be made. The publication makes no warranty,
expressed or implied, with respect to the materials contained within.

PREPARATION OF MANUSCRIPT

All manuscripts should be written in standard grammatical English using computer software (Franklin Gothic Book normal font, size 12,
with single spacing between lines) and should be saved as single DOC (Word) file. Main Research Articles and Brief Communications
will follow a similar format as outlined below while Review Articles will follow a variation on this (see below).

Main Research Articles are defined as being a substantial novel research study discussing the investigation of a clear hypothesis or
research question with appropriate methodologies (the use of more than one approach is encouraged) and adequately powered studies
and sample sizes. Noting the relevant sections (see below) there is no word limit on manuscripts of this type except for the Abstract
which should be a single unreferenced paragraph and no more than 350 words. There are no limits on the number of display items
(tables and/or figures) although authors should try to be concise and only include the most pertinent information. There are no
supplementary tables or figures and every effort should be made to include these in the main manuscript or alternatively reference
should be made in the appropriate locations of the manuscripts that such information will be available on request from the
corresponding authors. There is no limit on the number of references.

Brief Communications are a format that accommodates the reporting of high quality completed smaller scale studies (e.g. investigations
of rarer or less prevalent phenotypes and/or studies conducted within understudied or minority ethnic groups). This format is not for the
reporting of preliminary or incomplete findings and the review process is equally rigorous as that for Main Articles. The sections of a Brief
Communication follow those of Main Articles (see below) and there should not be additional sub-headings within these sections.

Review articles have a flexible format, are not of restricted length or reference number. Submissions of reviews must follow that of Main
Research Articles (see below) with the exception that appropriate headings be included for the main text of the manuscript.

Layout requirements for submissions of Main Research Articles or Brief Communications:

1.        cover letter
2.        title page
3.        abstract and keywords
4.        main text
5.        acknowledgements, if any
6.        Declaration of conflicts of interest, if any
7.        References
8.        tables, if any
9.        figure legends, if any
10.      figures, if any


Cover Letter

The cover letter should include name, degree, address, telephone, fax and email of the corresponding author. A statement that all
authors have contributed to, read and approved the final manuscript for submission should be included if there are multiple authors. Any
editorial or financial conflict of interest (e.g., consultancy, stock ownership, equity interests, patent or licensing agreements) should be
clearly disclosed in the cover letter. The disclosure statement must be submitted upon the acceptance. The cover letter should also be
used to provide up the relevant details of 4 potential reviewers and 2 non-reviewers for your manuscript giving appropriate explanations
for the latter. Finally, if this submission is following the solicitation or invitation of an Editorial Board member please state by whom.

Title Page

1.        a concise title;
2.        first name, middle initial, and last name of each author;
3.        name of the department and institutional affiliation of each author.
4.        the email address of each author.(*)
5.        a running title.

(*) AJSC will only use the email address of the designated corresponding author in the final published manuscript but will use all email
addresses supplied to copy in all authors as additional email respondents to the correspondences we routinely send to acknowledge
receipt of manuscripts, and final decisions made on submitted manuscripts. AJSC would also like, unless otherwise directed in the
manuscript covering letter, to use these contact details to announce the contents lists of future issues of AJSC and its sister journals! At
no stage will AJSC sell such email lists to parties external to the e-Century Publishing Corporation.

Abstract and Key Words

Abstract should not exceed 350 words that concisely summarize the study’s purpose, significant findings and conclusions. Include up to
10 key words or phrases at the end of the abstract.

Main Text

The main text should include Introduction, Materials and Methods, Results and Discussion. The Introduction should be succinct, clearly
stating the purpose and rationale of the study. In Materials and Methods, the procedures should be described in sufficient detail to allow
duplication by an independent observer. Results and Discussion should be divided. They should be written concisely and logically with
emphasis on novel findings and minimal repetition of text. For genetic association reports refer to specific information requirements.

Acknowledgements

All acknowledgements (if any) should be included at the end of the main text before references and may include grant and administrative
support.

References (Please download EndNote X Style or Reference Manager Output Style for AJSC)

Reference published in AJSC should begin on a new page, be single-spaced and numbered in order of citation in the text, including
citations in tables and figure legends. Complete author citation is required (use of "et al" is not acceptable). References should conform
to the style of the Journal. Examples follow:

Journals: [1]  Yin M, Hu Z, Tan D, Ajani JA, Wei Q. Molecular epidemiology of genetic susceptibility to gastric cancer: focus on single
nucleotide polymorphisms in gastric carcinogenesis. Am J Transl Res 2009;1:44-54.

Books: Fishman AP: Pulmonary Hypertension and Cor Pulmonale. Pulmonary Diseases and Disorders. Edited by Fishman AP. New
York, McGraw-Hill, 1988, pp. 999-1048

Web sites: Cite in text only using the appropriate URL. It is the author’s responsibility at the time of submission and
subsequent publication that the website address is relevant and functional.

In press: To be used only for papers accepted for publication. Cite as for journal with (in press) in place of volume and page numbers.

Personal Communications: to be used very sparingly and in the context of no more than one sentence of associated text.

Submitted papers/unpublished data: Cite in text only.

Tables

All tables should be created with Microsoft  Word Table Tool, single spacing between rows and cited consecutively in the main text by
Arabic numbers (Table 1, Table 2, etc). Include each table with a descriptive title on a separate page after the references. Provide
explanations for any nonstandard abbreviations in footnotes to the table.

All tables should be included in the Word File as the part of the complete manuscript after bibliography. Tables in image or other formats
are not acceptable. Authors are encouraged to split extremely large tables into multiple smaller ones to facilitate publication and
easiness to readers.

Figure Legends

Figure legends including figure number, a short title and detailed description should be embedded at the end of text file.

Figures

All figures should be cited consecutively in the main text by Arabic numbers (Figure 1, Figure 2, etc). All figures must be submitted in TIFF
or JPEG format as separate files labeled with the corresponding numbers. Photographs of a person should render them unidentifiable
or include their written permission. Any figures involving Copyright issues should conform to the Copyright policy.

Publication Fees

American Journal of Stem Cells is an open access journal which provides instant, worldwide and barrier-free access to the full-text of all
published articles. Publication charges allow the publisher to make the published material available for free to all interested online
readers.

The Publishing fee is $980 per article. Editorial board members are entitled to a 30% discount. This will be billed to the corresponding
author. There is no extra charge for color figures. Authors who do not have appropriate funds can apply to have the fee waived by
submitting a letter signed by the departmental chair to state such a fact. Editorial decisions are not contingent upon the ability to pay
publication charges.

Manuscript Submission

The journal invites submission of all original research and review articles, editorials, letter to the editor and meeting reports. AJSC will
also consider methodological articles. All manuscripts should be submitted via email to: editorial@AJSC.us and should be in
compliance with the author’s guidelines described above. Please visit submission for further information.
AJSC Copyright © 2011-present. All rights reserved. Published by e-Century Publishing Corporation, Madison, WI 53711, USA